|Title:||Polymorphs of donepezil hydrochloride and process for production|
|Abstract:||Donepezil hydrochloride, 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride, is provided here in the form of four polymorphs which are stable against heat and humidity in the pharmaceutical use. They can be industrially produced. They are specified by peaks in X-ray powder diffraction pattern and absorption peaks in infrared absorption spectra in potassium bromide.|
|Inventor(s):||Imai; Akio (Ibaraki, JP), Watanabe; Hideaki (Ibaraki, JP), Kajima; Takashi (Ibaraki, JP), Ishihama; Yasushi (Ibaraki, JP), Ohtsuka; Akiyo (Ibaraki, JP), Tanaka; Tomohide (Ibaraki, JP), Narabu; Yukio (Ibaraki, JP)|
|Assignee:||Eisai Co., Ltd. (Tokyo, JP)|
Patent Claim Types:|
see list of patent claims
|Compound; Process; Use; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||8-146293||Jun 07, 1996|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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