Details for Patent: 5,929,028

Summary for Patent: 5,929,028

Title:	Liquid gonadotropin containing formulations
Abstract:	The invention concerns a liquid gonadotropin-containing formulation characterised in that the formulation comprises a gonadotropin and stabilising amounts of a polycarboxylic acid or a salt thereof and of a thioether compound. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with the particular stabilizers in an aqueous solution. The preparations contain a sufficient amount of the polycarboxylic acid or a salt thereof, preferably sodium citrate, and a sufficient amount of the thioether compound, preferably methionine, to stabilize the protein. The preparations preferably also include a nonreducing disaccharide like sucrose, and a non-ionic surfactant.
Inventor(s):	Skrabanja; Arnold Titus Philip (An Nijmegen, NL), van den Oetelaar; Petrus Johannes Maria (Et Heesch, NL)
Assignee:	Akzo Nobel, N.V. (Arnhem, NL)
Application Number:	09/006,812
Patent Claim Types: see list of patent claims	Formulation; Compound; Process; Use;

Drugs Protected by US Patent 5,929,028

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

Foreign Priority and PCT Information for Patent: 5,929,028

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Netherlands	97200099	Jan 15, 1997

International Family Members for US Patent 5,929,028

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Argentina	011410
Austria	237348
Australia	5205998
Australia	736339
Brazil	9800323
Canada	2226803