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Last Updated: April 18, 2024

Details for Patent: 5,891,467

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Summary for Patent: 5,891,467

Title:	Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
Abstract:	The rate of release of encapsulated active compound from a multivesicular liposomal (MVL) formulation is modified by selection of a neutral lipid component. A family of MVL formulations containing different slow:fast release neutral lipid molar ratios display different release rates depending upon the molar ratio of the fast release neutral lipid to the slow release neutral lipid in each member. Incubation in plasma or a plasma-like medium at in vivo temperatures so as to obtain a release rate curve for each allows selection from among the members of the family of a liposomal formulation with a desired rate of release in vivo.
Inventor(s):	Willis; Randall C. (Solana Beach, CA)
Assignee:	Depotech Corporation (San Diego, CA)
Application Number:	08/792,566
Patent Claim Types: see list of patent claims	Use; Dosage form; Compound; Formulation;

Drugs Protected by US Patent 5,891,467

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 5,891,467

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	6317898	⤷ Try a Trial
Australia	731038	⤷ Try a Trial
Canada	2277956	⤷ Try a Trial
Canada	2564120	⤷ Try a Trial
Canada	2692302	⤷ Try a Trial
Canada	2851502	⤷ Try a Trial
Denmark	0971699	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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