Details for Patent: 5,814,639
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Summary for Patent: 5,814,639
Title: | Method for the synthesis, compositions and use of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds |
Abstract: | The present invention relates to a method of preparing the antiviral compounds 2'-deoxy-5-fluoro-3'thiacytidine (FTC) and various prodrug analogues of FTC from inexpensive precursors with the option of introducing functionality as needed; methods of using these compounds, particularly in the prevention and treatment of AIDS; and the compounds themselves. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds and related compounds. |
Inventor(s): | Liotta; Dennis C. (Stone Mountain, GA), Schinazi; Raymond F. (Decatur, GA), Choi; Woo-Baeg (North Brunswick, NJ) |
Assignee: | Emory University (Atlanta, GA) |
Application Number: | 08/017,820 |
Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 5,814,639
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