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Serving leading biopharmaceutical companies globally:

Dow
Colorcon
Citi
Daiichi Sankyo
Covington
US Army
Federal Trade Commission
Queensland Health
Boehringer Ingelheim
Farmers Insurance

Generated: February 25, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,792,477

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Summary for Patent: 5,792,477
Title: Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent
Abstract:A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymeric encapsulating binder, and an active agent having limited water solubility dissolved or dispersed in a solvent. An aqueous second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The two phases are separated. The discontinuous first phase is washed with water, or an aqueous solution of water and a solvent for residual solvent in the first phase, to reduce the level of residual solvent in the microparticles to less than about 2% by weight of the microparticles. Also disclosed are a microencapsulated drug prepared by the method for preparing biodegradable, biocompatible microparticles, and a pharmaceutical composition that includes biodegradable and biocompatible microparticles in a pharmaceutically acceptable carrier.
Inventor(s): Rickey; Michael E. (Loveland, OH), Ramstack; J. Michael (Lebanon, OH), Lewis; Danny H. (Hartselle, AL), Mesens; Jean (Wechelderzande, BE)
Assignee: Alkermes Controlled Therapeutics, Inc. II (Cambridge, MA) Janssen Pharmaceutica (BE)
Application Number:08/850,679
Patent Claim Types:
see list of patent claims
Process; Composition; Formulation; Use;

Drugs Protected by US Patent 5,792,477

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,792,477

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Turkey 9802258 ➤ Sign Up
Slovakia 283852 ➤ Sign Up
Slovakia 154198 ➤ Sign Up
Slovenia 1210942 ➤ Sign Up
Slovenia 904063 ➤ Sign Up
Russian Federation 2201214 ➤ Sign Up
Portugal 1210942 ➤ Sign Up
Portugal 904063 ➤ Sign Up
Poland 188550 ➤ Sign Up
Poland 329720 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Express Scripts
Cerilliant
QuintilesIMS
McKinsey
Deloitte
Daiichi Sankyo
Healthtrust
Covington

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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