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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Baxter
Federal Trade Commission
Accenture
Farmers Insurance
Deloitte
Citi
US Army
Merck

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,780,485

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Summary for Patent: 5,780,485
Title: Use of .alpha..sub.1c specific compounds to treat benign prostatic hyperplasia
Abstract:A method of treating benign prostatic hyperplasia in a subject which comprises administering to the subject a therapeutically effective amount of a compound which binds to a human .alpha..sub.1C adrenergic receptor with a binding affinity greater than ten-fold higher than the binding affinity with which the compound binds to a human .alpha..sub.1A adrenergic receptor, a human .alpha..sub.1B adrenergic receptor, and a human histamine H.sub.1 receptor, and, binds to a human .alpha..sub.2 adrenergic receptor with a binding affinity which is greater than ten-fold lower than the binding affinity with which the compound binds to such .alpha..sub.1C adrenergic receptor. Compounds meeting these criteria are provided.
Inventor(s): Gluchowski; Charles (Wayne, NJ), Forray; Carlos C. (Waldwick, NJ), Chiu; George (Bridgewater, NJ), Branchek; Theresa A. (Teaneck, NJ), Wetzel; John M. (Elmwood Park, NJ), Hartig; Paul R. (Princeton, NJ)
Assignee: Synaptic Pharmaceutical Corporation (Paramus, NJ)
Application Number:08/415,681
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 5,780,485

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Accenture
Johnson and Johnson
Julphar
QuintilesIMS
Cantor Fitzgerald
UBS
Cerilliant
Harvard Business School

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