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Serving leading biopharmaceutical companies globally:

Merck
Daiichi Sankyo
Healthtrust
Chubb
Mallinckrodt
Express Scripts
Farmers Insurance
Colorcon
Dow
Citi

Generated: February 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,780,485

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Summary for Patent: 5,780,485
Title: Use of .alpha..sub.1c specific compounds to treat benign prostatic hyperplasia
Abstract:A method of treating benign prostatic hyperplasia in a subject which comprises administering to the subject a therapeutically effective amount of a compound which binds to a human .alpha..sub.1C adrenergic receptor with a binding affinity greater than ten-fold higher than the binding affinity with which the compound binds to a human .alpha..sub.1A adrenergic receptor, a human .alpha..sub.1B adrenergic receptor, and a human histamine H.sub.1 receptor, and, binds to a human .alpha..sub.2 adrenergic receptor with a binding affinity which is greater than ten-fold lower than the binding affinity with which the compound binds to such .alpha..sub.1C adrenergic receptor. Compounds meeting these criteria are provided.
Inventor(s): Gluchowski; Charles (Wayne, NJ), Forray; Carlos C. (Waldwick, NJ), Chiu; George (Bridgewater, NJ), Branchek; Theresa A. (Teaneck, NJ), Wetzel; John M. (Elmwood Park, NJ), Hartig; Paul R. (Princeton, NJ)
Assignee: Synaptic Pharmaceutical Corporation (Paramus, NJ)
Application Number:08/415,681
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 5,780,485

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,780,485

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2240495 ➤ Sign Up
Australia 5602994 ➤ Sign Up
Australia 680457 ➤ Sign Up
Australia 700304 ➤ Sign Up
Australia 7684894 ➤ Sign Up
Canada 2148839 ➤ Sign Up
Canada 2187773 ➤ Sign Up
European Patent Office 0667769 ➤ Sign Up
European Patent Office 0758894 ➤ Sign Up
Israel 107581 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Moodys
Express Scripts
Johnson and Johnson
Cantor Fitzgerald
UBS
Teva
Argus Health
US Army

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