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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Argus Health
Chinese Patent Office
McKinsey
Julphar
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AstraZeneca
Medtronic
US Department of Justice
UBS

Generated: February 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,767,285

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Summary for Patent: 5,767,285
Title: Linkers useful for the synthesis of conjugates of methyltrithio antitumor agents
Abstract:This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.
Inventor(s): Hamann; Philip Ross (Garnerville, NY), Hinman; Lois (N. Tarrytown, NY), Hollander; Irwin (Monsey, NY), Holcomb; Ryan (Glen Rock, NJ), Hallett; William (New City, NY), Tsou; Hwei-Ru (New City, NY), Weiss; Martin J. (Ft. Lee, NJ)
Assignee: American Cyanamid Company (Madison, NJ)
Application Number:08/462,939
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 5,767,285

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,767,285

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Israel 129953 ➤ Try a Free Trial
Canada 2150785 ➤ Try a Free Trial
Cyprus 2334 ➤ Try a Free Trial
Germany 69528016 ➤ Try a Free Trial
Denmark 0689845 ➤ Try a Free Trial
European Patent Office 0689845 ➤ Try a Free Trial
Spain 2181752 ➤ Try a Free Trial
Finland 952720 ➤ Try a Free Trial
Finland 117690 ➤ Try a Free Trial
Israel 113984 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Covington
Johnson and Johnson
Chinese Patent Office
Argus Health
Daiichi Sankyo
Cipla
Mallinckrodt
Federal Trade Commission
Colorcon

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