Details for Patent: 5,723,606

Summary for Patent: 5,723,606

Title:	Condensed benzazepine derivative and pharmaceutical composition thereof
Abstract:	This invention relates to nitrogen-containing aromatic 5-membered ring-condensed benzazepine derivatives represented by the general formula (I) ##STR1## (symbols in the formula have the following meanings; ring B: a nitrogen-containing aromatic 5-membered ring having at least 1 nitrogen atom and optionally one oxygen or sulfur atom, which may optionally have substituent(s), R.sup.1 and R.sup.2 : these may be the same or different from each other and each represents a hydrogen atom, a halogen atom, a lower alkyl group, an amino group which may optionally be substituted by lower alkyl group(s), or a lower alkoxy group, A: a single bond; a group represented by the formula n: 0 or an integer of from 1 to 3, R.sup.3 and R.sup.4 : these may be the same or different from each other and each represents a hydrogen atom, a lower alkyl group (provided that R.sup.3 and R.sup.4 may together form a lower alkylene group having 2 to 7 carbon atoms), and ring C: a benzene ring which may optionally have substituent(s)) and salts thereof; to pharmaceutical compositions which contain these compounds as an active ingredient and to intermediates which are useful in synthesizing these compounds. The compounds of this invention are useful as arginine vasopressin antagonists.
Inventor(s):	Tanaka; Akihiro (Ibaraki, JP), Koshio; Hiroyuki (Ibaraki, JP), Taniguchi; Nobuaki (Ibaraki, JP), Matsuhisa; Akira (Ibaraki, JP), Sakamoto; Ken-ichiro (Ibaraki, JP), Yamazaki; Atsuki (Ibaraki, JP), Yatsu; Takeyuki (Ibaraki, JP)
Assignee:	Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:	08/586,686
Patent Claim Types: see list of patent claims	Compound; Composition; Use;

Drugs Protected by US Patent 5,723,606

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

Foreign Priority and PCT Information for Patent: 5,723,606

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	5-180435	Jul 21, 1993

PCT Information
PCT Filed	July 19, 1994	PCT Application Number:	PCT/JP94/01183
PCT Publication Date:	February 02, 1995	PCT Publication Number:	WO95/03305

International Family Members for US Patent 5,723,606

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	239726
Austria	277003
Australia	3990697
Australia	683483
Australia	7195794