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Details for Patent: 5,681,818

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Summary for Patent: 5,681,818

Title: Therapeutic uses of human somatomedin carrier proteins
Abstract:This invention relates to polypeptides that are human somatomedin carrier protein subunits and to processes for producing them. The carrier protein subunits bind to human somatomedin-like polypeptides, also known as insulin-like growth factors. The process involves preparation from a human serum fraction, Cohn IV-1, by a molecule of various chromatographic steps. This invention also relates to DNA molecules encoding human somatomedin carrier protein-like polypeptides, recombinant DNA molecules, hosts, processes for producing carrier protein-like polypeptides, human somatomedin carrier protein-like polypeptides produced using those molecules, hosts and processes. The invention relates to DNA molecules and their expression in appropriate hosts. The recombinant DNA molecules contain DNA molecules that code for polypeptides which have a biological activity of the human carrier protein or a human carrier protein subunit capable of binding somatomedins. The DNA molecules, recombinant DNA molecules, hosts, and processes of this invention may be used in the production of polypeptides useful in a variety of therapeutic, diagnostic, and other useful applications.
Inventor(s): Spencer; Emerald Martin (San Francisco, CA), Talkington-Verser; Carol (San Rafael, CA)
Assignee: Celtrix Pharmaceuticals, Inc. (Santa Clara, CA)
Application Number:08/320,123
Patent Claim Types:
see list of patent claims
Use; Composition;

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International Patent Family for Patent: 5,681,818

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria155793► subscribe
Austria90690► subscribe
Australia1702088► subscribe
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