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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Johnson and Johnson
Chinese Patent Office

Generated: November 18, 2017

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Details for Patent: 5,654,010

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Summary for Patent: 5,654,010

Title: Composition for sustained release of human growth hormone
Abstract:A composition, and methods of forming and using said composition, for the sustained release of biologically active, stabilized human growth hormone (hGH). The sustained release composition of this invention comprises a polymeric matrix of a biocompatible polymer and particles of biologically active, stabilized hGH, wherein said particles are dispersed within the biocompatible polymer. The method of the invention for producing a composition for the sustained release of biologically active hGH, includes dissolving a biocompatible polymer in a polymer solvent to form a polymer solution, dispersing particles of biologically active, stabilized hGH in the polymer solution, and then solidifying the polymer to form a polymeric matrix containing a dispersion of said hGH particles. The method for using a composition of the invention is a method for providing a therapeutically effective blood level of biologically active, non-aggregated hGH in a subject for a sustained period. In this method, a subject is administered an effective dose of the sustained release composition of the present invention. The method of using the sustained release composition of the present invention comprises providing a therapeutically effective blood level of biologically active, non-aggregated human growth hormone in a subject for a sustained period by administering to the subject a dose of said sustained release composition.
Inventor(s): Johnson; OluFunmi Lily (Cambridge, MA), Ganmukhi; Medha M. (Wexford, PA), Bernstein; Howard (Cambridge, MA), Auer; Henry (Belmont, MA), Khan; M. Amin (Dowington, PA)
Assignee: Alkermes, Inc. (Cambridge, MA)
Application Number:08/473,544
Patent Claim Types:
see list of patent claims
Composition; Use;

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International Patent Family for Patent: 5,654,010

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0831787► Subscribe
Australia698016► Subscribe
Australia705451► Subscribe
Australia705968► Subscribe
Australia706180► Subscribe
Australia708756► Subscribe
Australia2822295► Subscribe
Australia5683594► Subscribe
Australia5972496► Subscribe
Australia6034196► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

US Army
Queensland Health
Farmers Insurance
Chinese Patent Office
Fish and Richardson
Cantor Fitzgerald

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