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Serving leading biopharmaceutical companies globally:

Dow
Fish and Richardson
Fuji
Farmers Insurance
Boehringer Ingelheim
Federal Trade Commission
Daiichi Sankyo
Cantor Fitzgerald
Moodys
AstraZeneca

Generated: January 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,654,010

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Summary for Patent: 5,654,010
Title: Composition for sustained release of human growth hormone
Abstract:A composition, and methods of forming and using said composition, for the sustained release of biologically active, stabilized human growth hormone (hGH). The sustained release composition of this invention comprises a polymeric matrix of a biocompatible polymer and particles of biologically active, stabilized hGH, wherein said particles are dispersed within the biocompatible polymer. The method of the invention for producing a composition for the sustained release of biologically active hGH, includes dissolving a biocompatible polymer in a polymer solvent to form a polymer solution, dispersing particles of biologically active, stabilized hGH in the polymer solution, and then solidifying the polymer to form a polymeric matrix containing a dispersion of said hGH particles. The method for using a composition of the invention is a method for providing a therapeutically effective blood level of biologically active, non-aggregated hGH in a subject for a sustained period. In this method, a subject is administered an effective dose of the sustained release composition of the present invention. The method of using the sustained release composition of the present invention comprises providing a therapeutically effective blood level of biologically active, non-aggregated human growth hormone in a subject for a sustained period by administering to the subject a dose of said sustained release composition.
Inventor(s): Johnson; OluFunmi Lily (Cambridge, MA), Ganmukhi; Medha M. (Wexford, PA), Bernstein; Howard (Cambridge, MA), Auer; Henry (Belmont, MA), Khan; M. Amin (Dowington, PA)
Assignee: Alkermes, Inc. (Cambridge, MA)
Application Number:08/473,544
Patent Claim Types:
see list of patent claims
Composition; Use;

Drugs Protected by US Patent 5,654,010

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,654,010

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 195652 ➤ Subscribe
Austria 204468 ➤ Subscribe
Austria 222500 ➤ Subscribe
Australia 2822295 ➤ Subscribe
Australia 4275597 ➤ Subscribe
Australia 4630893 ➤ Subscribe
Australia 5683594 ➤ Subscribe
Australia 5972496 ➤ Subscribe
Australia 6034196 ➤ Subscribe
Australia 6146996 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

QuintilesIMS
Accenture
Teva
Harvard Business School
Baxter
Fish and Richardson
Fuji
Medtronic
Daiichi Sankyo

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