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Serving leading biopharmaceutical companies globally:

AstraZeneca
Accenture
Cerilliant
Daiichi Sankyo
Queensland Health
Teva
Colorcon
Healthtrust
Cipla
Deloitte

Generated: January 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,641,803

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Summary for Patent: 5,641,803
Title: Methods for administration of taxol
Abstract:Taxol dosages of about 135 mg/m.sup.2 or greater are administered via infusions of less than 6 hours duration; the method makes it possible to provide taxol infusions on an out-patient basis to patients who do not otherwise require hospitalization. In a preferred embodiment, about 135 mg/m.sup.2 of taxol in a cremaphor emulsion is infused over a 3 hour duration, following patient pretreatment with steroids, antihistamines, and H.sub.2 -receptor antagonists sufficient to prevent fatal anaphylactic-like reactions, and preferably sufficient to reduce the occurrence of severe anaphylactic-like reactions in greater than 90% of patients treated. In an alternative embodiment, between 135 mg/.sup.2 and about 175 mg/m.sup.2 of taxol is provided in a 3-hour infusion, following protreatment to minimize hypersensitivity responses. A method for rechallenging patients with taxol after episodes of acute hypersensitivity reactions is also disclosed, thus enabling patients to continue taxol therapy who would otherwise be deprived of treatment.
Inventor(s): Carretta; Renzo Mauro (Madison, CT), Eisenhauer; Elizabeth (Kingston, CA), Rozencweig; Marcel (Spendford, CT)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:08/544,594
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 5,641,803

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,641,803

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2086874 ➤ Subscribe
Switzerland 686868 ➤ Subscribe
Cyprus 2049 ➤ Subscribe
Germany 4325927 ➤ Subscribe
Germany 69310634 ➤ Subscribe
Denmark 65293 ➤ Subscribe
Denmark 0584001 ➤ Subscribe
European Patent Office 0584001 ➤ Subscribe
European Patent Office 0783885 ➤ Subscribe
European Patent Office 0783886 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Cipla
Medtronic
US Army
Cantor Fitzgerald
Johnson and Johnson
Farmers Insurance
Mallinckrodt
Accenture
Citi

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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