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Serving leading biopharmaceutical companies globally:

McKinsey
Baxter
Chinese Patent Office
Medtronic
McKesson
Harvard Business School
AstraZeneca
QuintilesIMS
Moodys
Teva

Generated: February 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,633,352

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Summary for Patent: 5,633,352
Title: Biosynthetic human growth hormone
Abstract:A desired protein having the formula: wherein a) A is Lys or Arg, and B and C are arbitrary amino acids, or b) A is an arbitrary amino acid different from Pro, Lys and Arg, and B and/or C is Pro, is produced from a biosynthetically formed amino acid extended protein having the formula: wherein A, B, C and P are as defined above, and X is an amino acid sequence with an even number of amino acids, of which the first one, seen from the N-terminal end, is different from Lys and Arg, all other uneven amino acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Thus, e.g. hGH without content of Met-hGH may be produced by the process.
Inventor(s): Dalb.o slashed.ge; Henrik (Virum, DK), Pedersen; John (Kokkedal, DK), Christensen; Thorkild (Aller.o slashed.d, DK), Ringsted; J.o slashed.rli W. (Br.o slashed.ndby, DK), Jessen; Torben E. (Holbaek, DK)
Assignee: Novo Nordisk A/S (DK)
Application Number:08/402,286
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 5,633,352

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,633,352

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Denmark5493/82Dec 10, 1982
Denmark556/85Feb 07, 1985

International Patents Family Members for US Patent 5,633,352

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 30246 ➤ Try a Free Trial
Austria 52807 ➤ Try a Free Trial
Australia 2331784 ➤ Try a Free Trial
Australia 5514586 ➤ Try a Free Trial
Australia 590258 ➤ Try a Free Trial
Germany 3374070 ➤ Try a Free Trial
Germany 3671245 ➤ Try a Free Trial
Denmark 2192 ➤ Try a Free Trial
Denmark 344884 ➤ Try a Free Trial
Denmark 55685 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
UBS
Queensland Health
Chubb
AstraZeneca
Express Scripts
Mallinckrodt
Medtronic
Cipla

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