|Title:||Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituent and processes for preparing thereof|
|Abstract:||The present invention relates to a novel quinolone compound having an excellent antibacterial activity. More specifically, the present invention relates to a novel quinoline(naphthyridine)carboxylic acid derivative represented by the following formula (I), which has an 4-aminomethyl-3-oximepyrrolidine substituent on 7-position of the quinolone nucleus and shows a superior antibacterial activity in contrast to the known quinolone antibacterial agents having a weak activity against gram-positive bacterial strains and also has a broad antibacterial spectrum and a highly improved pharmacokinetic property: ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and Q are defined as described in the specification.|
|Inventor(s):||Hong; Chang Y. (Daejeon, KR), Kim; Young K. (Kyungki-do, KR), Chang; Jay H. (Daejeon, KR), Kim; Se H. (Seoul, KR), Choi; Hoon (Daejeon, KR), Nam; Do H. (Daejeon, KR), Kwak; Jin H. (Daejeon, KR), Jeong; Yi N. (Daejeon, KR), Oh; Jeong I. (Daejeon, KR), Kim; Mu Y. (Daejeon, KR)|
|Assignee:||LG Chemical Ltd. (Seoul, KR)|
Patent Claim Types:|
see list of patent claims
|Compound; Composition; Dosage form;|
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