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|Title:||Esters of thienyl carboxylic acids and amino alcohols and their quaternization products|
|Abstract:||Compounds of the formula ##STR1## of which, in exemplary compounds, the thienyl group is attached via the 2-position and: (a) A is 3.alpha.-(6.beta., 7.beta.-epoxy)-tropanyl methobromide and R.sub.1 is 2-thienyl; (b) A is 3.alpha.-(6, 7dehydro)-tropanyl methobromide and R.sub.1 is 2-thienyl; (c) A is 3.beta.-tropanyl methobromide and R.sub.1 is 2-thienyl; and, (d) A is 3.alpha.-(N-isopropyl)-nortropanyl methobromide and R.sub.1 is cyclopentyl. These are anticholinergics. Administered by inhalation, they are useful for the treatment of chronic obstructive bronchitis or slight to moderately severe asthma. Administered by the intravenous or oral routes, they are useful for the treatment of vagally induced sinus bradycardia.|
|Inventor(s):||Banholzer; Rolf (Ingelheim am Rheim, DE), Bauer; Rudolf (Wiesbaden, DE), Reichl; Richard (Ingelheim am Rheim, DE)|
|Assignee:||Boehringer Ingelheim GmbH (Ingelheim am Rhein, DE)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Composition; Dosage form;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Germany||39 31 041.8||Sep 16, 1989|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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