|Title:||Amine polymer sequestrant and method of cholesterol depletion|
|Abstract:||An amine polymer includes first and second substituents bound to amines of the polymer. The first substituent includes a hydrophobic moiety. The second substituent includes a quaternary amine-containing moiety. A method for binding bile salts of bile acids in a mammal includes orally administering to the mammal a therapeutically-effective amount of the amine polymer.|
|Inventor(s):||Mandeville, III; W. Harry (Lynnfield, MA), Holmes-Farley; Stephen R. (Arlington, MA)|
|Assignee:||GelTex Pharmaceuticals, Inc. (Waltham, MA)|
Patent Claim Types:|
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