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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Argus Health

Generated: November 17, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,591,762

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Summary for Patent: 5,591,762

Title: Benzimidazoles useful as angiotensin-11 antagonists
Abstract:Disclosed herein are angiotensin-II antagonists of the formula ##STR1## wherein R.sub.1 is, other than hydrogen and, inter alia, halogen, lower alkyl or cycloalkyl; R.sub.2 is, inter alia, optionally substituted benzimidazol-2-yl, 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl, butanesultam-1-yl, imidazol-4-yl, and tetrahydobenzimidazol-2-yl; R.sub.3 is, inter alia, lower alkyl; and, R.sub.4 is an acidic group, such as carboxyl or tetrazolyl. An exemplary compound is: (a) 4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)-benzimidazol-1-yl] methyl]-biphenyl-2-carboxylic acid.
Inventor(s): Hauel; Norbert (Schemmerhofen, DE), Narr, deceased; Berthold (late of Biberach, DE), Ries; Uwe (Biberch, DE), van Meel; Jacobus C. A. (Mittelbiberach, DE), Wienen; Wolfgang (Biberach/Rissegg, DE), Entzeroth; Michael (Warthausen, DE)
Assignee: Dr. Karl Thomae GmbH (Biberach an der Riss, DE)
Application Number:08/457,204
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

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Foreign Priority and PCT Information for Patent: 5,591,762

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany41 03 492.9Feb 06, 1991
Germany41 17 121.7May 25, 1991
Germany41 37 812.1Nov 16, 1991
Germany42 01 554.5Jan 22, 1992
Germany42 12 250.3Apr 11, 1992
Germany42 19 782.1Jun 17, 1992
Germany42 24 133.2Jul 22, 1992
Germany42 24 752.7Jul 27, 1992
Germany42 25 756.5Aug 04, 1992

International Patent Family for Patent: 5,591,762

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
China1083812► Subscribe
China1050122► Subscribe
Czechoslovakia9200306► Subscribe
Czech Republic287607► Subscribe
Czech Republic9203944► Subscribe
Czech Republic9300621► Subscribe
Czech Republic9301449► Subscribe
Germany4103492► Subscribe
Germany4117121► Subscribe
Germany4137812► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

US Department of Justice
US Army
Farmers Insurance
Daiichi Sankyo
Cantor Fitzgerald
Boehringer Ingelheim

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