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Generated: January 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,591,762

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Summary for Patent: 5,591,762
Title: Benzimidazoles useful as angiotensin-11 antagonists
Abstract:Disclosed herein are angiotensin-II antagonists of the formula ##STR1## wherein R.sub.1 is, other than hydrogen and, inter alia, halogen, lower alkyl or cycloalkyl; R.sub.2 is, inter alia, optionally substituted benzimidazol-2-yl, 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl, butanesultam-1-yl, imidazol-4-yl, and tetrahydobenzimidazol-2-yl; R.sub.3 is, inter alia, lower alkyl; and, R.sub.4 is an acidic group, such as carboxyl or tetrazolyl. An exemplary compound is: (a) 4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)-benzimidazol-1-yl] methyl]-biphenyl-2-carboxylic acid.
Inventor(s): Hauel; Norbert (Schemmerhofen, DE), Narr, deceased; Berthold (late of Biberach, DE), Ries; Uwe (Biberch, DE), van Meel; Jacobus C. A. (Mittelbiberach, DE), Wienen; Wolfgang (Biberach/Rissegg, DE), Entzeroth; Michael (Warthausen, DE)
Assignee: Dr. Karl Thomae GmbH (Biberach an der Riss, DE)
Application Number:08/457,204
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 5,591,762

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,591,762

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany41 03 492.9Feb 06, 1991
Germany41 17 121.7May 25, 1991
Germany41 37 812.1Nov 16, 1991
Germany42 01 554.5Jan 22, 1992
Germany42 12 250.3Apr 11, 1992
Germany42 19 782.1Jun 17, 1992
Germany42 24 133.2Jul 22, 1992
Germany42 24 752.7Jul 27, 1992
Germany42 25 756.5Aug 04, 1992

International Patents Family Members for US Patent 5,591,762

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
China 1083812 ➤ Subscribe
China 1050122 ➤ Subscribe
Czechoslovakia 9200306 ➤ Subscribe
Czech Republic 287607 ➤ Subscribe
Czech Republic 9203944 ➤ Subscribe
Czech Republic 9300621 ➤ Subscribe
Czech Republic 9301449 ➤ Subscribe
Germany 4103492 ➤ Subscribe
Germany 4117121 ➤ Subscribe
Germany 4137812 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Novartis
Express Scripts
Harvard Business School
Julphar
Teva
Baxter
US Department of Justice
Healthtrust
Farmers Insurance

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