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Generated: August 20, 2019

DrugPatentWatch Database Preview

Details for Patent: 5,543,152

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Summary for Patent: 5,543,152
Title: Sphingosomes for enhanced drug delivery
Abstract:Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.
Inventor(s): Webb; Murray S. (Vancouver, CA), Bally; Marcel B. (Bowen Island, CA), Mayer; Lawrence D. (North Vancouver, CA)
Assignee: Inex Pharmaceuticals Corporation (Vancouver, CA)
Application Number:08/263,603
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Delivery; Compound; Process; Formulation;

Drugs Protected by US Patent 5,543,152

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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International Family Members for US Patent 5,543,152

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 248586 ➤ Sign Up
Australia 2709495 ➤ Sign Up
Canada 2193502 ➤ Sign Up
Germany 69531701 ➤ Sign Up
European Patent Office 0804159 ➤ Sign Up
Spain 2206510 ➤ Sign Up
Japan 3270478 ➤ Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Covington
Mallinckrodt
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Fish and Richardson

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