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Generated: December 14, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,474,978

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Summary for Patent: 5,474,978

Title: Insulin analog formulations
Abstract:The present invention discloses a human insulin analog hexamer complex and formulations. More specifically, the present invention relates to various parenteral formulations, which comprise: human insulin analogs in a hexamer conformation, zinc ions, and at least three molecules of a phenolic derivative selected from the group consisting of m-cresol, phenol, or a mixture of m-cresol and phenol. The formulation provides a rapid onset of action.
Inventor(s): Bakaysa; Diane L. (Indianapolis, IN), Brems; David N. (Indianapolis, IN), Frank; Bruce H. (Indianapolis, IN), Havel; Henry A. (Indianapolis, IN), Pekar; Allen H. (Indianapolis, IN)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:08/260,634
Patent Claim Types:
see list of patent claims
Formulation; Composition; Use;

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International Patent Family for Patent: 5,474,978

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Greece1003004► Subscribe
Greece950100229► Subscribe
United Kingdom2291427► Subscribe
United Kingdom9512038► Subscribe
France2741078► Subscribe
France2721214► Subscribe
Finland118207► Subscribe
Finland952931► Subscribe
Spain2091727► Subscribe
Denmark173015► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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