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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Argus Health
AstraZeneca
Merck
Covington
Baxter
Federal Trade Commission
Julphar
US Department of Justice

Generated: June 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,474,783

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Summary for Patent: 5,474,783
Title: Solubility parameter based drug delivery system and method for altering drug saturation concentration
Abstract:The method of adjusting the saturation concentration of a drug in a transdermal composition for application to the dermis, which comprises mixing polymers having differing solubility parameters, so as to modulate the delivery of the drug. This results in the ability to achieve a predetermined permeation rate of the drug into and through the dermis. In one embodiment, a dermal composition of the present invention comprises a drug, an acrylate polymer, and a polysiloxane. The dermal compositions can be produced by a variety of methods known in the preparation of drug-containing adhesive preparations, including the mixing of the polymers, drug, and additional ingredients in solution, followed by removal of the processing solvents. The method and composition of this invention permit selectable loading of the drug into the dermal formulation and adjustment of the delivery rate of the drug from the composition through the dermis, while maintaining acceptable shear, tack, and peel adhesive properties.
Inventor(s): Miranda; Jesus (Miami, FL), Sablotsky; Steven (Miami, FL)
Assignee: Noven Pharmaceuticals, Inc. (Miami, FL)
Application Number:07/722,342
Patent Claim Types:
see list of patent claims
Delivery; Composition;

Drugs Protected by US Patent 5,474,783

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Chubb
Farmers Insurance
Johnson and Johnson
US Department of Justice
Mallinckrodt
US Army
Cipla
Fish and Richardson

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