Last Updated: November 8, 2026

Details for Patent: 5,424,471

Name: Drug Patent Intelligence for US Patent 5424471
Creator: DrugPatentWatch
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Summary for Patent: 5,424,471

Title:	Crystalline amifostine compositions and methods of the preparation and use of same
Abstract:	The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4 DEG C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.
Inventor(s):	Paul E. Kennedy, Roger A. Rajewski, John M. Baldoni
Assignee:	MedImmune LLC
Application Number:	US08/099,298
Patent Claim Types: see list of patent claims	Use; Composition; Formulation; Compound; Process; Dosage form;

Drugs Protected by US Patent 5,424,471

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 5,424,471

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Australia	4796693	⤷ Start Trial
Australia	681858	⤷ Start Trial
Canada	2120133	⤷ Start Trial
China	1070370	⤷ Start Trial
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