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Generated: March 21, 2019

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Details for Patent: 5,420,319

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Summary for Patent: 5,420,319
Title: Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same
Abstract:Disclosed is cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and no toxicity and exhibiting anticancer performance, as shown in the below Formula. Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex of the invention possesses high optical purity or 99.94% or more e.e. and a melting point of 198.3.degree. to 199.7.degree. C. The complex is synthesized employing as starting material trans-1-1,2-cyclohexamediamine or a derivative of the trans-1-1,2-cyclohexanediamine optically resoluted by means of a high performance liquid chromatography. ##STR1##
Inventor(s): Okamoto; Koji (Kanagawa, JP), Nakanishi; Chihiro (Kanagawa, JP), Taniuchi; Junichi (Kanagawa, JP), Ohnishi; Junji (Kanagawa, JP), Komoda; Yasunobu (Kanagawa, JP)
Assignee: Tanaka Kikinzoku Kogyo K.K. (JP)
Application Number:08/117,892
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,420,319
Patent Claim Types:
see list of patent claims
Compound; Process;

Drugs Protected by US Patent 5,420,319

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate

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Foreign Priority and PCT Information for Patent: 5,420,319

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan5-142824May 21, 1993

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