Generated: April 26, 2017
|Title:||Pulmonary surfactant protein and related polypeptides|
|Abstract:||The present invention discloses useful peptides and synthetic pulmonary surfactants, as well as methods of making and using same. In a preferred embodiment, a synthetic pulmonary surfactant comprises one or more pharmaceutically acceptable phospholipids admixed with a polypeptide comprising at least 10 amino acid residues and no more than about 60 amino acid residues, said polypeptide including a sequence having alternating hydrophobic and hydrophilic amino acid residue regions. In other embodiments, a surfactant peptide has an amino acid residue sequence selected from the group consisting of KLLLLKLLLLKLLLLKLLLLK, KLLLLLLLLKLLLLLLLLKLL, and KKLLLLLLLKKLLLLLLLKKL.|
|Inventor(s):||Cochrane; Charles G. (La Jolla, CA), Revak; Susan D. (San Diego, CA)|
|Assignee:||The Scripps Research Institute (La Jolla, CA)|
Patent Claim Types:|
see list of patent claims
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|European Patent Office||0350506||► Subscribe|
|European Patent Office||0590006||► Subscribe|
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