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Details for Patent: 5,364,620
Summary for Patent: 5,364,620
Title: | Controlled absorption diltiazem formulation for once daily administration |
Abstract: | A diltiazem pellet formulation for oral administration comprises a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid, and a multi-layer membrane surrounding the core and containing a major proportion of a pharmaceutically acceptable film-forming, water insoluble synthetic polymer and a minor proportion of a pharmaceutically acceptable film-forming, water soluble synthetic polymer. The number of layers in the membrane and the ratio of the water soluble to water insoluble polymer being effective to permit release of the diltiazem from the pellet at a rate allowing controlled absorption thereof over a twenty four hour period following oral administration. |
Inventor(s): | Geoghegan; Edward J. (Athlone, IE), Mulligan; Seamus (Athlone, IE), Panoz; Donald E. (Tuckerstown, BN) |
Assignee: | Elan Corporation, Plc (Westmeath, IE) |
Application Number: | 07/921,459 |
Patent Claim Types: see list of patent claims | Use; Formulation; |
Drugs Protected by US Patent 5,364,620
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Patent Submitted |
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Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Patent Submitted |
International Patents Family Members for US Patent 5,364,620
Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Spain | 2194832 | ➤ Try a Free Trial | |||
Ireland | 833057 | ➤ Try a Free Trial | |||
Switzerland | 662507 | ➤ Try a Free Trial | |||
Germany | 3485023 | ➤ Try a Free Trial | |||
Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |