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Generated: June 26, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,266,331

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Summary for Patent: 5,266,331

Title: Controlled release oxycodone compositions
Abstract:A solid controlled release, oral dosage form, the dosage form comprising a therapeutically effective amount of oxycodone or a salt thereof in a matrix wherein the dissolution rate in vitro of the dosage form, when measured by the USP Paddle Method of 100 rpm in 900 ml aqueous buffer (pH between 1.6 and 7.2) at 37.degree. C. is between 12.5% and 42.5% (by weight) oxycodone released after 1 hour, between 25% and 55% (by weight) oxycodone released after 2 hours, between 45% and 75% (by weight) oxycodone released after 4 hours and between 55% and 85% (by weight) oxycodone released after 6 hours, the in vitro release rate being independent of pH between pH 1.6 and 7.2 and chosen such that the peak plasma level of oxycodone obtained in vivo occurs between 2 and 4 hours after administration of the dosage form.
Inventor(s): Oshlack; Benjamin (New York, NY), Minogue; John J. (Mount Vernon, NY), Chasin; Mark (Manalpan, NJ)
Assignee: Euroceltique, S.A. (LU)
Application Number:07/800,549
Patent Claim Types:
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Formulation; Compound; Dosage form; Composition; Process;

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International Patent Family for Patent: 5,266,331

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria144418► Subscribe
Austria226822► Subscribe
Austria261725► Subscribe
Austria261726► Subscribe
Austria261727► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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