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Serving hundreds of leading biopharmaceutical companies globally:

US Department of Justice
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Teva
Queensland Health
Johnson and Johnson
Dow
US Army
Fish and Richardson
Express Scripts

Generated: June 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,266,325

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Summary for Patent: 5,266,325
Title: Preparation of homogeneous hydrogel copolymers
Abstract:A method is provided for the preparation of homogeneous copolymers having a redetermined equilibrium water content (EWC) value formed by the addition polymerization of a mixture of ethylenically unsaturated monomer A and ethylenically unsaturated monomer B, for example, 2-hydroxyethyl methacrylate and hydroxypropyl methacrylate. The method requires determining the EWC values of the hydrogel homopolymer of hydrophilic monomer A (homopolymer A) and the hydrogel homopolymer of hydrophilic monomer B (homopolymer B); determining the relationship of the EWC values of the homogeneous copolymers AB versus the chemical composition of said copolymers AB; selecting the targeted EWC value and determining the chemical composition of copolymer AB having the targeted EWC value; forming a polymerizable mixture of monomer A and monomer B in amounts sufficient to yield copolymer AB having the targeted EWC value; and effect the polymerization reaction to yield copolymer AB characterized by the targeted EWC value. A method is also provided for the preparation of a delivery device including a drug contained in the reservoir of the hydrogel of copolymer AB, said device being characterized by its capability of eluting or releasing the drug through the hydrogel membrane to a delivery environment at a predetermined rate. There is also disclosed a sterilized kit containing a trocar or hypodermic needle/syringe and the aforesaid drug delivery device having a cylindrical shape with a rounded or bullet-like extremity.
Inventor(s): Kuzma; Petr (Monmouth Junction, NJ), Moro; Daniel G. (Randolph, NJ), Quandt; Harry (North Middletown, NJ)
Assignee: Hydro Med Science Division of National Patent Development Corp. (New York, NY)
Application Number:07/621,346
Patent Claim Types:
see list of patent claims
Use; Composition; Delivery; Device;

Drugs Protected by US Patent 5,266,325

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 5,266,325

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 149345 ➤ Try a Free Trial
Australia 1018392 ➤ Try a Free Trial
Australia 651654 ➤ Try a Free Trial
Canada 2059377 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Queensland Health
Julphar
McKesson
Citi
Mallinckrodt
Medtronic
McKinsey
Dow
Colorcon

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