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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Boehringer Ingelheim
Farmers Insurance
Baxter
Chubb
Merck
Colorcon
Mallinckrodt
McKinsey

Generated: May 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,225,445

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Summary for Patent: 5,225,445
Title: Phenethanolamine derivatives having .beta..sub.2 -adrenoreceptor selective stimulant action
Abstract:Phenethanolamine derivatives are disclosed of formula ##STR1## wherein m is 2 to 8; n is 1 to 7 provided that m+n is 4 to 12; Ar is phenyl or phenyl substituted by one or two halogen atoms, alkyl or alkoxy groups or by an alkylenedioxy group; R.sup.1 and R.sup.2 are hydrogen or alkyl provided that the sum total of carbon atoms in R.sup.1 and R.sup.2 is not more than 4; and the physiologically acceptable salts and solvates thereof. The compounds have a selective stimulant action at .beta..sub.2 -adrenoreceptors and may be used inter alia in the treatment of diseases associated with reversible airways obstructions such as asthma and chronic bronchitis. The compounds may be formulated in conventional manner as pharmaceutical compositions with physiologically acceptable carriers or excipients. The compounds may be prepared, for example by alkylation of an amine: ##STR2## where R.sup.3, R.sup.5 and R.sup.6 is hydrogen or a protecting group, followed by removal of any protecting group.
Inventor(s): Skidmore; Ian F. (Welwyn, GB2), Lunts; Lawrence H. C. (Broxbourne, GB2), Finch; Harry (Hitchin, GB2), Naylor; Alan (Royston, GB2)
Assignee: Glaxo Group Ltd. (London)
Application Number:07/837,783
Patent Claim Types:
see list of patent claims
Use; Compound;

Drugs Protected by US Patent 5,225,445

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 5,225,445

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8310477Apr 18, 1983
United Kingdom8317087Jun 23, 1983
United Kingdom8329560Nov 04, 1983
United Kingdom8401809Jan 25, 1984

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
McKesson
Cipla
Johnson and Johnson
Medtronic
QuintilesIMS
Federal Trade Commission
Chubb
Dow

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