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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
Deloitte
Johnson and Johnson
McKinsey
Healthtrust
Medtronic
Chubb
QuintilesIMS
Baxter
Queensland Health

Generated: February 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,213,804

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Summary for Patent: 5,213,804
Title: Solid tumor treatment method and composition
Abstract:A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50 .mu.g agent/.mu.mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Inventor(s): Martin; Francis J. (San Francisco, CA), Woodle; Martin C. (Menlo Park, CA), Redemann; Carl (Walnut Creek, CA), Yau-Young; Annie (Palo Alto, CA)
Assignee: Liposome Technology, Inc. (Menlo Park, CA)
Application Number:07/642,321
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Compound; Use;

Drugs Protected by US Patent 5,213,804

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 5,213,804

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 115401 ➤ Try a Free Trial
Austria 122229 ➤ Try a Free Trial
Austria 142483 ➤ Try a Free Trial
Austria 152614 ➤ Try a Free Trial
Australia 5323194 ➤ Try a Free Trial
Australia 642679 ➤ Try a Free Trial
Australia 6527294 ➤ Try a Free Trial
Australia 654120 ➤ Try a Free Trial
Australia 6637490 ➤ Try a Free Trial
Australia 6898291 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Mallinckrodt
Merck
Harvard Business School
US Army
Express Scripts
US Department of Justice
Federal Trade Commission
Dow

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