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Serving leading biopharmaceutical companies globally:

US Army
Queensland Health
US Department of Justice

Generated: October 19, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,213,804

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Summary for Patent: 5,213,804

Title: Solid tumor treatment method and composition
Abstract:A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50 .mu.g agent/.mu.mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Inventor(s): Martin; Francis J. (San Francisco, CA), Woodle; Martin C. (Menlo Park, CA), Redemann; Carl (Walnut Creek, CA), Yau-Young; Annie (Palo Alto, CA)
Assignee: Liposome Technology, Inc. (Menlo Park, CA)
Application Number:07/642,321
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Compound; Use;

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International Patent Family for Patent: 5,213,804

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada2146565► Subscribe
Canada2067178► Subscribe
Canada2067133► Subscribe
Germany19675048► Subscribe
Germany69015207► Subscribe
Germany69019366► Subscribe
Germany69304685► Subscribe
Germany69310527► Subscribe
Denmark0496835► Subscribe
Denmark0632719► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Fish and Richardson
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Federal Trade Commission

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