Details for Patent: 5,196,404
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Summary for Patent: 5,196,404
Title: | Inhibitors of thrombin |
Abstract: | This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes. |
Inventor(s): | Maraganore; John M. (Concord, MA), Fenton, II; John W. (Malden Bridge, NY), Kline; Toni (New York, NY) |
Assignee: | Biogen, Inc. (Cambridge, MA) Health Research, Inc. (Albany, NY) |
Application Number: | 07/549,388 |
Patent Claim Types: see list of patent claims | Compound; Use; Composition; Device; |
Drugs Protected by US Patent 5,196,404
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International Family Members for US Patent 5,196,404
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 137246 | ⤷ Try a Trial | |||
Austria | 193325 | ⤷ Try a Trial | |||
Australia | 1362192 | ⤷ Try a Trial | |||
Australia | 6284190 | ⤷ Try a Trial | |||
Australia | 652125 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |