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Last Updated: March 28, 2024

Details for Patent: 5,196,404


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Summary for Patent: 5,196,404
Title: Inhibitors of thrombin
Abstract:This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
Inventor(s): Maraganore; John M. (Concord, MA), Fenton, II; John W. (Malden Bridge, NY), Kline; Toni (New York, NY)
Assignee: Biogen, Inc. (Cambridge, MA) Health Research, Inc. (Albany, NY)
Application Number:07/549,388
Patent Claim Types:
see list of patent claims
Compound; Use; Composition; Device;

Drugs Protected by US Patent 5,196,404

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 5,196,404

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 137246 ⤷  Try a Trial
Austria 193325 ⤷  Try a Trial
Australia 1362192 ⤷  Try a Trial
Australia 6284190 ⤷  Try a Trial
Australia 652125 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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