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Last Updated: June 14, 2021

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Details for Patent: 5,196,404

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Summary for Patent: 5,196,404
Title: Inhibitors of thrombin
Abstract:This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
Inventor(s): Maraganore; John M. (Concord, MA), Fenton, II; John W. (Malden Bridge, NY), Kline; Toni (New York, NY)
Assignee: Biogen, Inc. (Cambridge, MA) Health Research, Inc. (Albany, NY)
Application Number:07/549,388
Patent Claim Types:
see list of patent claims
Compound; Use; Composition; Device;

Drugs Protected by US Patent 5,196,404

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 5,196,404

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 137246   Get Started Free
Austria 193325   Get Started Free
Australia 1362192   Get Started Free
Australia 6284190   Get Started Free
Australia 652125   Get Started Free
Australia 659828   Get Started Free
Bulgaria 60759   Get Started Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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