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Last Updated: March 28, 2024

Details for Patent: 5,192,741


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Summary for Patent: 5,192,741
Title: Sustained and controlled release of water insoluble polypeptides
Abstract:There is disclosed a pharaceutical composition for sustained and controlled release of drug over an extended period of time comprising a polylactide, a copolymer of lactic and glycolic acid, a mixture of such polymers and a water-insoluble peptide which, when placed in an aqueous physiologically-type environment releases the peptide in continuous manner for a period of at least one week, and with an initial release for the first twenty-four hours of not more than 30% of the total amount released. There is thus provided the control of the release pattern and in general a decrease of the initial burst effect.
Inventor(s): Orsolini; Piero (Martigny, CH), Mauvernay; Rolland-Yves (Lausanne, CH), Deghenghi; Romano (Lausanne, CH)
Assignee: Debiopharm S.A. (Lausanne, CH)
Application Number:07/247,060
Patent Claim Types:
see list of patent claims
Composition; Process; Dosage form; Delivery; Formulation;

Drugs Protected by US Patent 5,192,741

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,192,741

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8722134Sep 21, 1987

International Family Members for US Patent 5,192,741

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 397035 ⤷  Try a Trial
Austria A223488 ⤷  Try a Trial
Australia 2232688 ⤷  Try a Trial
Australia 611944 ⤷  Try a Trial
Belgium 1001685 ⤷  Try a Trial
Canada 1326438 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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