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Last Updated: October 28, 2021

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Details for Patent: 5,192,741

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Summary for Patent: 5,192,741
Title: Sustained and controlled release of water insoluble polypeptides
Abstract:There is disclosed a pharaceutical composition for sustained and controlled release of drug over an extended period of time comprising a polylactide, a copolymer of lactic and glycolic acid, a mixture of such polymers and a water-insoluble peptide which, when placed in an aqueous physiologically-type environment releases the peptide in continuous manner for a period of at least one week, and with an initial release for the first twenty-four hours of not more than 30% of the total amount released. There is thus provided the control of the release pattern and in general a decrease of the initial burst effect.
Inventor(s): Orsolini; Piero (Martigny, CH), Mauvernay; Rolland-Yves (Lausanne, CH), Deghenghi; Romano (Lausanne, CH)
Assignee: Debiopharm S.A. (Lausanne, CH)
Application Number:07/247,060
Patent Claim Types:
see list of patent claims
Composition; Process; Dosage form; Delivery; Formulation;

Drugs Protected by US Patent 5,192,741

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,192,741

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8722134Sep 21, 1987

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Johnson and Johnson

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