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Details for Patent: 5,126,375

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Summary for Patent: 5,126,375

Title: Phenethanolamine derivatives
Abstract:Phenethanolamine derivatives are disclosed of formula ##STR1## wherein m is 2 to 8; n is 1 to 7 provided that m+n is 4 to 12; Ar is phenyl or phenyl substituted by one or two halogen atoms, alkyl or alkoxy groups or by an alkylenedioxy group; R.sup.1 and R.sup.2 are hydrogen or alkyl provided that the sum total of carbon atoms in R.sup.1 and R.sup.2 is not more than 4; and the physiologically acceptable salts and solvates thereof. The compounds have a selective stimulant action at .beta..sub.2 -adrenoreceptors and may be used inter alia in the treatment of diseases associated with reversible airways obstructions such as asthma and chronic bronchitis. The compounds may be formulated in conventional manner as pharmaceutical compositions with physiologically acceptable carriers or excipients. The compounds may be prepared, for example by alkylation of an amine: ##STR2## where R.sup.3, R.sup.5 and R.sup.6 is hydrogen or a protecting group, followed by removal of any protecting group.
Inventor(s): Skidmore; Ian F. (Herts, GB2), Lunts; Lawrence H. C. (Herts, GB2), Finch; Harry (Herts, GB2), Naylor; Alan (Herts, GB2)
Assignee: Glaxo Group Ltd. (London, GB)
Application Number:07/619,899
Patent Claim Types:
see list of patent claims
Compound; Composition;

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Foreign Priority and PCT Information for Patent: 5,126,375

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan8310477Apr 18, 1983
Japan8317087Jun 23, 1983
Japan8329568Nov 04, 1983

International Patent Family for Patent: 5,126,375

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina244199► subscribe
Argentina245687► subscribe
Argentina247721► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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