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Generated: April 27, 2017

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Details for Patent: 5,045,321

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Summary for Patent: 5,045,321

Title: Stabilized pharmaceutical composition and its production
Abstract:The pharmaceutical composition of the invention, which comprises a benzimidazole compound of the formula ##STR1## wherein R.sup.1 is hydrogen, alkyl, halogen, cyano, carboxy, carboalkoxy, carboalkoxyalkyl, carbamoyl, carbamoylaklyl, hydroxy, alkoxy, hydroxyalkyl, trifluoromethyl, acyl, carbamoyloxy, nitro, acyloxy, aryl, aryloxy, alkylthio or alkylsulfinyl, R.sup.2 is hydrogen, alkyl, acyl, carboalkoxy, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, alkylcarbonylmethyl, alkoxycarbonylmethyl or alkylsulfonyl, R.sup.3 and R.sup.5 are the same or different and each is hydrogen, alkyl, alkoxy or alkoxyalkoxy, R.sup.4 is hydrogen, alkyl, alkoxy which may optionally be fluorinated, or alkoxyalkoxy, and m is an integer of 0 through 4, and a basic inorganic salt of magnesium and/or a basic inorganic salt of calcium, is physically stable.
Inventor(s): Makino; Tadashi (Osaka, JP), Tabata; Tetsuro (Osaka, JP), Hirai; Shin-ichiro (Kyoto, JP)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:07/014,303
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Dosage form;

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Foreign Priority and PCT Information for Patent: 5,045,321

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan61-29567Feb 13, 1986
Japan61-38059Feb 21, 1986

International Patent Family for Patent: 5,045,321

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany3750431► Subscribe
Germany3751845► Subscribe
Germany3780045► Subscribe
European Patent Office0237200► Subscribe
European Patent Office0423748► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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