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Last Updated: March 29, 2024

Details for Patent: 5,019,583


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Summary for Patent: 5,019,583
Title: N-phenyl-N-(4-piperidinyl)amides useful as analgesics
Abstract:N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X is a member selected from the group consisting of alkoxy-carbonyl-lower alkyl, lower alkyl-carbonyloxy-lower alkyl, alkenyloxy-carbonyl-lower alkyl, and (C.sub.1-2)alkoxy-(C.sub.1-2)-alkoxy-carbonyl-lower alkyl, and Ar, R, R.sup.1 and R.sup.2 are defined hereinafter, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activity having relatively short durations of analgesic action. The invention embraces the compounds (I), pharmaceutical compositions of (I) and methods of providing analgesia with (I). Also included are certain novel intermediates for making (I).
Inventor(s): Feldman; Paul L. (Durham, NC), James; Michael K. (Raleigh, NC), Brackeen; Marcus F. (Durham, NC), Johnson; Michael R. (Chapel Hill, NC), Leighton; Harry J. (Chapel Hill, NC)
Assignee: Glaxo Inc. (Research Triangle Park, NC)
Application Number:07/448,497
Patent Claim Types:
see list of patent claims
Compound; Composition; Dosage form; Use;

Drugs Protected by US Patent 5,019,583

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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