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|Title:||Oral sustained release pharmaceutical formulation and process|
|Abstract:||A pharmaceutical sustained release tablet or tablet layer is formed by making a wet granulation, using povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with a pharmaceutical active, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered erosion promotor, e.g. pregelantinized starch, additional wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a slow release of the pharmaceutical active.|
|Inventor(s):||Radebaugh; Galen W. (Chester, NJ), Murtha; John L. (Holland, PA), Glinecke; Robert (Glenside, PA)|
|Assignee:||McNeil-PPC, Inc. (Milltown, NJ)|
Patent Claim Types:|
see list of patent claims
|Dosage form; Process; Composition; Formulation;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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