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Generated: June 27, 2017

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Details for Patent: 4,963,590

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Summary for Patent: 4,963,590

Title: Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
Abstract:Pharmacologically active catechol derivatives of formula I ##STR1## wherein R.sub.1 and R.sub.2 independently comprise hydrogen, alkyl, acyl, optionally substituted aroyl, lower alkylsulfonyl or alkylcabamoyl or taken together form a lower alkylidene or cycloalkylidene, X comprises an electronegative substituent such as halogen, nitro, cyano, lower alkylsulfonyl, sulfonamido, aldehyde, caboxyl or trifluoromethyl and R.sub.3 comprises hydrogen, halogen, hydroxy alkyl, amino, nitro, cyano, trifluoromethyl, lower alkylsulfonyl, sulfonamide, aldehyde, alkyl carbonyl, aralkylidene carbonyl or carboxyl or a group selected from ##STR2## wherein R.sub.4 comprises hydrogen, alkyl, cyano, carboxyl or acyl and R.sub.5 comprises hydrogen, cyano, carboxyl, alkoxycarbonyl, carboxyalkenyl, nitro, acyl, optionally substituted aroyl or heteroaroyl, hydroxyalkyl or carboxyalkyl or R.sub.4 and R.sub.5 together form a five to seven membered substituted cycloalkanone ring; wherein n is 0-1 and m is 0-7 and R comprises hydroxy, alkyl, carboxyalkyl, optionally substituted alkene, alkoxy or optionally substituted amino; ##STR3## wherein R.sub.8 and R.sub.9 independently comprise hydrogen or one of the following optionally substituted groups; alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, or together form an optionally substituted piperidyl group; wherein R.sub.10 comprises a substituted alkyl group.
Inventor(s): Backstrom; Reijo J. (Helsinki, FI), Heinola; Kalevi E. (Javenpaa, FI), Honkanen; Erkki J. (Vantaa, FI), Kaakkola; Seppo K. (Helsinki, FI), Kairisalo; Pekka J. (Helsinki, FI), Linden; Inge-Britt Y. (Helsinki, FI), Mannisto; Pekka T. (Helsinki, FI), Nissinen; Erkki A. O. (Espoo, FI), Pohto; Pentti (Helsinki, FI), Pippuri; Aino K. (Espoo, FI), Pystynen; Jarmo J. (Espoo, FI)
Assignee: Orion-yhtyma Oy (FI)
Application Number:07/126,911
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

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Foreign Priority and PCT Information for Patent: 4,963,590

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Finland864875Nov 28, 1986

International Patent Family for Patent: 4,963,590

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
German Democratic Republic281375► Subscribe
Ireland873242► Subscribe
Hungary206073► Subscribe
HungaryT45473► Subscribe
CroatiaP921250► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving 500+ biopharmaceutical companies globally:

McKinsey
Moodys
Accenture
Argus Health
UBS
Cantor Fitzgerald
Colorcon
Daiichi Sankyo
Baxter
Medtronic

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