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|Title:||Cyclic amine compounds with activity against acetylcholinesterase|
|Abstract:||A cyclic amine compound is defined by the formula: ##STR1## in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is --(CHR22)r--, R22 being H or methyl, --CO--(CHR22)r--, .dbd.(CH--CH.dbd.CH)b--, .dbd.CH--(CH2)c-- or .dbd.(CH--CH)d.dbd. and the ring including T and Q is piperidine. The compound is useful to treat senile dementia.|
|Inventor(s):||Sugimoto; Hachiro (Ushiku, JP), Tsuchiya; Yutaka (Fort Lee, NJ), Higurashi; Kunizou (Tokyo, JP), Karibe; Norio (Tsukuba, JP), Iimura; Youichi (Tsukuba, JP), Sasaki; Atsushi (Tsukuba, JP), Yamanishi; Yoshiharu (Ryugasaki, JP), Ogura; Hiroo (Tsuchiura, JP), Araki; Shin (Tsukuba, JP), Kosasa; Takashi (Tsukuba, JP), Kubota; Atsuhiko (Tsukuba, JP), Kosasa; Michiko (Tsukuba, JP), Yamatsu; Kiyomi (Kamakura, JP)|
|Assignee:||Eisai Co., Ltd. (Tokyo, JP)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||62-155058||Jun 22, 1987|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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