Details for Patent: 4,877,805

Summary for Patent: 4,877,805

Title:	Methods for treatment of sundamaged human skin with retinoids
Abstract:	Various effects of photoaging or sundamage of skin including impairment of differentiation of epidermal epithelial cells and loss of collagen fibers, abnormal changes in elastic fibers and deterioration of small blood vessels in the dermis of the skin are retarded by applying topically to the epidermis in a maintenance therapy program effective amounts of retinoids including retinoid derivatives and stereoisomers thereof such that epithelial growths are substantially reduced and prevented and the skin substantially regains and maintains its firmness, turgor and elasticity. Moreover, with persistent treatment dermal blood cells and vessels increase and the epidermis and dermis thicken, resulting in improved ability of the skin to sense, resist and recover from irritation or injury. Further, hyperpigmentation, lines and wrinkles due to aging are reduced and prevented. The treatment is particularly useful for human facial skin and preferably applied in amounts insufficient to cause excessive irritation.
Inventor(s):	Kligman; Albert M. (Philadelphia, PA)
Assignee:
Application Number:	07/205,057
Patent Claim Types: see list of patent claims	Use; Composition; Formulation;

Drugs Protected by US Patent 4,877,805

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International Family Members for US Patent 4,877,805

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	5289686
Australia	598454
Australia	599135