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Last Updated: August 12, 2020

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Details for Patent: 4,863,742

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Summary for Patent: 4,863,742
Title: Controlled absorption pharmaceutical composition
Abstract:A controlled absorption verapamil containing pellet formulation for oral adminstration comprises a core of a powder mixture containing verapamil or a pharmaceutically acceptable salt thereof and an organic acid and a polymeric material, said core comprising layers of said powder mixture and said polymeric material superimposed one upon the other and said polymeric material being present in an amount effective to ensure that all of said powder mixture is coated into said core and a multi-layer membrane surrounding said core, the number of layers in said membrane and the ratio of the various polymers comprising the membrane being effective to permit release of the verapamil from the pellet at a rate allowing controlled absorption thereof over a 24 hour period following oral administration, said rate being measured in vivo and having a Tmax between 6 and 16 hours.
Inventor(s): Panoz; Donald E. (Tuckerstown, BM), Geoghegan; Edward J. (Westmeath, IE)
Assignee: Elan Corporation PLC (Athlone, IE)
Application Number:07/064,765
Patent Claim Types:
see list of patent claims
Formulation; Dosage form; Composition; Process; Use;

Drugs Protected by US Patent 4,863,742

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 4,863,742

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Ireland1661/86Jun 20, 1986

International Family Members for US Patent 4,863,742

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 72975   Start Trial
Australia 599385   Start Trial
Australia 7452887   Start Trial
Germany 3776982   Start Trial
European Patent Office 0250267   Start Trial
Spain 2039440   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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