Details for Patent: 4,863,742

Summary for Patent: 4,863,742

Title:	Controlled absorption pharmaceutical composition
Abstract:	A controlled absorption verapamil containing pellet formulation for oral adminstration comprises a core of a powder mixture containing verapamil or a pharmaceutically acceptable salt thereof and an organic acid and a polymeric material, said core comprising layers of said powder mixture and said polymeric material superimposed one upon the other and said polymeric material being present in an amount effective to ensure that all of said powder mixture is coated into said core and a multi-layer membrane surrounding said core, the number of layers in said membrane and the ratio of the various polymers comprising the membrane being effective to permit release of the verapamil from the pellet at a rate allowing controlled absorption thereof over a 24 hour period following oral administration, said rate being measured in vivo and having a Tmax between 6 and 16 hours.
Inventor(s):	Panoz; Donald E. (Tuckerstown, BM), Geoghegan; Edward J. (Westmeath, IE)
Assignee:	Elan Corporation PLC (Athlone, IE)
Application Number:	07/064,765
Patent Claim Types: see list of patent claims	Formulation; Dosage form; Composition; Process; Use;

Drugs Protected by US Patent 4,863,742

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

Foreign Priority and PCT Information for Patent: 4,863,742

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Ireland	1661/86	Jun 20, 1986

International Family Members for US Patent 4,863,742

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	72975
Australia	599385
Australia	7452887
Germany	3776982
European Patent Office	0250267