Details for Patent: 4,863,742
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Summary for Patent: 4,863,742
Title: | Controlled absorption pharmaceutical composition |
Abstract: | A controlled absorption verapamil containing pellet formulation for oral adminstration comprises a core of a powder mixture containing verapamil or a pharmaceutically acceptable salt thereof and an organic acid and a polymeric material, said core comprising layers of said powder mixture and said polymeric material superimposed one upon the other and said polymeric material being present in an amount effective to ensure that all of said powder mixture is coated into said core and a multi-layer membrane surrounding said core, the number of layers in said membrane and the ratio of the various polymers comprising the membrane being effective to permit release of the verapamil from the pellet at a rate allowing controlled absorption thereof over a 24 hour period following oral administration, said rate being measured in vivo and having a Tmax between 6 and 16 hours. |
Inventor(s): | Panoz; Donald E. (Tuckerstown, BM), Geoghegan; Edward J. (Westmeath, IE) |
Assignee: | Elan Corporation PLC (Athlone, IE) |
Application Number: | 07/064,765 |
Patent Claim Types: see list of patent claims | Formulation; Dosage form; Composition; Process; Use; |
Drugs Protected by US Patent 4,863,742
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,863,742
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Ireland | 1661/86 | Jun 20, 1986 |
International Family Members for US Patent 4,863,742
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 72975 | ⤷ Sign Up | |||
Australia | 599385 | ⤷ Sign Up | |||
Australia | 7452887 | ⤷ Sign Up | |||
Germany | 3776982 | ⤷ Sign Up | |||
European Patent Office | 0250267 | ⤷ Sign Up | |||
Spain | 2039440 | ⤷ Sign Up | |||
Greece | 3003978 | ⤷ Sign Up | |||
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