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Details for Patent: 4,863,737

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Summary for Patent: 4,863,737

Title: Compositions and methods of manufacture of compressed powder medicaments
Abstract:Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored confectionary base and to compress or otherwise attach the solid confectionary mixture onto an appliance or holder. Employing the present invention, the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a compressed powder "candy " matrix. The pH and pKa of the powder matrix can be modified to increase the absorption of the drug through the mucosal tissues.
Inventor(s): Stanley; Theodore H. (Salt Lake City, UT), Hague; Brian (West Valley, UT)
Assignee: University of Utah (Salt Lake City, UT)
Application Number:07/060,045
Patent Claim Types:
see list of patent claims
Use; Delivery; Formulation; Composition;

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International Patent Family for Patent: 4,863,737

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria116131<disabled in preview>
Austria129148<disabled in preview>
Austria138562<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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