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|Title:||Oral sustained release acetaminophen formulation and process|
|Abstract:||An acetaminophen-sustained release tablet or tablet layer is formed by making a wet granulation, using Povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with acetaminophen, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered erosion promoter, e.g. pregelatinized starch, wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a slow release of the acetaminophen.|
|Inventor(s):||Radebaugh; Galen W. (Maple Glen, PA), Murtha; John L. (Holland, PA), Glinecke; Robert (Glenside, PA)|
|Assignee:||McNeilab, Inc. (Spring House, PA)|
Patent Claim Types:|
see list of patent claims
|Compound; Dosage form; Process; Composition; Formulation;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
| This preview shows a limited data set|
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