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|Abstract:||An oil-in-water type cream comprising (a) 0.01 to 0.5% by weight of hydrocortisone butyrate proponate, (b) 5 to 50% by weight of a higher paraffinic hydrocarbon, (c) 3 to 15% by weight of a surface-active agent, (d) 30 to 65% by weight of purified water, (e) not more than 20% by weight of a monohydric higher alcohol, (f) not more than 20% by weight of a dihdyric or trihydric alcohol, and (g) a pharmaceutically acceptable acid in an amount required to adjust the pH of the cream to a value in the range of 3.5 to 6.5 when it is diluted with water to 20 times its volume.|
|Inventor(s):||Takashima; Yasuji (Saitama, JP), Tanaka; Shigeo (Saitama, JP), Tsunoda; Kenji (Saitama, JP), Kawamata; Ichirou (Saitama, JP), Murayama; Hiroshi (Tokyo, JP)|
|Assignee:||Taisho Pharmaceutical Co., Ltd. (Tokyo, JP)|
Patent Claim Types:|
see list of patent claims
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||58-14302||Jan 31, 1983|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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