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Generated: October 16, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,746,680

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Summary for Patent: 4,746,680

Title: Therapeutic agents
Abstract:Compounds of formula I ##STR1## in which R.sub.1 is C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.3-7 cycloalkyl, cycloalkylalkyl or optionally substituted phenyl; R.sub.2 is H or C.sub.1-3 alkyl; R.sub.3 and/or R.sub.4 are H, formyl, C.sub.1-3 alkyl, C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, C.sub.3-7 cycloalkyl or R.sub.3 and R.sub.4 together with the nitrogen atom form a heterocyclic ring system; R.sub.5 and/or R.sub.6 are H, halo, CF.sub.3, C.sub.1-3 alkyl, C.sub.1-3 alkoxy, C.sub.1-3 alkylthio or R.sub.5 and R.sub.6 together with the carbon atoms to which they are attached form a second benzene ring show therapeutic activity in the treatment of depression. Pharmaceutical compositions and processes for preparing compounds of formula I are disclosed.
Inventor(s): Jeffery; James E. (Nottingham, GB), Kozlik; Antonin (Nottingham, GB), Wilmshurst; Eric C. (Nottingham, GB)
Assignee: The Boots Company p.l.c. (GB2)
Application Number:06/725,206
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

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Foreign Priority and PCT Information for Patent: 4,746,680

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8110709Apr 06, 1981

International Patent Family for Patent: 4,746,680

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Jordan1184► Subscribe
JapanS57181043► Subscribe
JapanH0141132► Subscribe
Kenya3753► Subscribe
South Korea900000274► Subscribe
Lithuania2518► Subscribe
Luxembourg84070► Subscribe
Italy1235758► Subscribe
France2504920► Subscribe
United Kingdom2098602► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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