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Serving leading biopharmaceutical companies globally:

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Generated: November 24, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,631,286

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Summary for Patent: 4,631,286

Title: 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
Abstract:There are disclosed compounds having the formula ##STR1## wherein X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, NHCOR.sub.2 wherein R.sub.2 is loweralkyl, or a group of the formula NR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl; R and R.sub.1 are independently hydrogen, loweralkyl, phenylloweralkyl, phenylloweralkyl in which the phenyl group is substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl, diphenylloweralkyl or diphenylloweralkyl in which one or both phenyl groups are substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl; Y is C.dbd.O or CR.sub.5 OH wherein R.sub.5 is hydrogen or loweralkyl; Z is CH.sub.2 or C.dbd.CR.sub.6 R.sub.7 wherein R.sub.6 and R.sub.7 are independently hydrogen or loweralkyl; or Y and Z taken together is CR.sub.5 .dbd.CH wherein CR.sub.5 and CH correspond to Y and Z respectively; an optical antipode thereof, or a pharmaceutically acceptable acid addition salt thereof, which are useful for enhancing memory, methods for synthesizing them, and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound.
Inventor(s): Shutske; Gregory M. (Somerset, NJ), Pierrat; Frank A. (Somerset, NJ)
Assignee: Hoechst-Roussel Pharmaceuticals Inc. (Somerville, NJ)
Application Number:06/664,731
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

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International Patent Family for Patent: 4,631,286

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina247394► Subscribe
Austria63903► Subscribe
Australia3823489► Subscribe
Australia4903885► Subscribe
Australia589141► Subscribe
Australia615768► Subscribe
Canada1292744► Subscribe
Czech Republic9104092► Subscribe
Germany3582995► Subscribe
Denmark141992► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Argus Health
Daiichi Sankyo
Queensland Health
Fish and Richardson

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