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Serving leading biopharmaceutical companies globally:

Moodys
AstraZeneca
Federal Trade Commission
Dow
Teva
Covington
Fuji
Chinese Patent Office
Citi
Colorcon

Generated: February 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,631,286

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Summary for Patent: 4,631,286
Title: 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
Abstract:There are disclosed compounds having the formula ##STR1## wherein X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, NHCOR.sub.2 wherein R.sub.2 is loweralkyl, or a group of the formula NR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl; R and R.sub.1 are independently hydrogen, loweralkyl, phenylloweralkyl, phenylloweralkyl in which the phenyl group is substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl, diphenylloweralkyl or diphenylloweralkyl in which one or both phenyl groups are substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl; Y is C.dbd.O or CR.sub.5 OH wherein R.sub.5 is hydrogen or loweralkyl; Z is CH.sub.2 or C.dbd.CR.sub.6 R.sub.7 wherein R.sub.6 and R.sub.7 are independently hydrogen or loweralkyl; or Y and Z taken together is CR.sub.5 .dbd.CH wherein CR.sub.5 and CH correspond to Y and Z respectively; an optical antipode thereof, or a pharmaceutically acceptable acid addition salt thereof, which are useful for enhancing memory, methods for synthesizing them, and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound.
Inventor(s): Shutske; Gregory M. (Somerset, NJ), Pierrat; Frank A. (Somerset, NJ)
Assignee: Hoechst-Roussel Pharmaceuticals Inc. (Somerville, NJ)
Application Number:06/664,731
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 4,631,286

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 4,631,286

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 247394 ➤ Sign Up
Austria 63903 ➤ Sign Up
Australia 3823489 ➤ Sign Up
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Australia 589141 ➤ Sign Up
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Canada 1292744 ➤ Sign Up
Czech Republic 9104092 ➤ Sign Up
Germany 3582995 ➤ Sign Up
Denmark 141992 ➤ Sign Up
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Serving hundreds of leading biopharmaceutical companies globally:

Federal Trade Commission
Cerilliant
AstraZeneca
Merck
Express Scripts
McKinsey
Mallinckrodt
QuintilesIMS
Daiichi Sankyo

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