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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Boehringer Ingelheim
Express Scripts
Farmers Insurance
Argus Health
AstraZeneca
Moodys
Cipla
Baxter

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,517,181

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Summary for Patent: 4,517,181
Title: Mammalian PGRF
Abstract:PGRF has been synthesized. The invention provides synthetic peptides which are extremely potent in stimulating the release of pituitary GH in mammals and which have the formula: ##STR1## wherein R is OH or NH.sub.2, R.sub.34 is Ser or Ala, R.sub.38 is Arg or Ser, R.sub.40 is Ala or Arg and R.sub.41 is Arg, Arg-Ala, Arg-Ala-Arg, Arg-Ala-Arg-Leu or des-R.sub.41. These peptides or biologically active fragments thereof, or analogs thereof having well-known substitutions and/or additions, as well as nontoxic salts of any of the foregoing, may be administered therapeutically to mammals, including humans, and may be used diagnostically.
Inventor(s): Ling; Nicholas C. (San Diego, CA), Esch; Frederick S. (Oceanside, CA), Bohlen; Peter (Encinitas, CA), Brazeau, Jr.; Paul E. (San Diego, CA), Guillemin; Roger C. L. (La Jolla, CA)
Assignee: The Salk Institute for Biological Studies (San Diego, CA)
Application Number:06/418,248
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,517,181

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 4,517,181

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 17737 ➤ Try a Free Trial
Australia 1584383 ➤ Try a Free Trial
Australia 548590 ➤ Try a Free Trial
Bulgaria 37523 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Dow
QuintilesIMS
Covington
Farmers Insurance
Merck
Johnson and Johnson
US Army
Colorcon
Moodys

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