|Title:||Antihypertensive diuretic combination composition and associated method|
|Abstract:||A novel combination pharmaceutical composition is described, together with a method for making the same, wherein the pharmaceutically active ingredients are separately milled and then formed into separate granules, and only thereafter blended together to form the combination composition. The method for achieving this novel combination composition is also described. In particular, a novel combination composition of triamterene and hydrochlorothiazide having improved bioavailability and novel effectiveness to prevent or eliminate hypokalemic side effects is also described.|
|Inventor(s):||Blume; Cheryl D. (Morgantown, WV), Bonner; Paul H. (Morgantown, WV)|
|Assignee:||Mylan Pharmaceuticals, Inc. (Morgantown, WV)|
Patent Claim Types:|
see list of patent claims
|Use; Composition; Dosage form; Formulation;|
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