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Generated: December 14, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,439,423

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Summary for Patent: 4,439,423

Title: Chymopapain and method for its use
Abstract:An improved method for treating an intervertebral spinal disc in a mammalian subject which disc exhibits an abnormal condition, characterized by a reduced risk of toxic effect to the subject is provided which comprises, injecting in said disc an amount of a pharmaceutically acceptable solution of a purified chymopapain essentially free of proteolytically inactive and/or toxic protein components, said purified chymopapain being used in an amount sufficient to selectively dissolve the nucleus pulposus of said disc. Pharmaceutical compositions are also provided for said method which include a purified proteolytically active lyophilized chymopapain, essentially free of proteolytically inactive and toxic components, and an activating amount of a pharmaceutically acceptable reducing agent.
Inventor(s): Smith; William S. (Libertyville, IL)
Assignee: Smith Laboratories, Inc. (Rosemont, IL)
Application Number:06/263,197
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation;

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International Patent Family for Patent: 4,439,423

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina229179► Subscribe
Australia555487► Subscribe
Australia8364182► Subscribe
Canada1179263► Subscribe
Canada1183478► Subscribe
Germany3278934► Subscribe
Denmark163525► Subscribe
Denmark215482► Subscribe
European Patent Office0065395► Subscribe
Spain512113► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Federal Trade Commission
Chinese Patent Office

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