|Title:||Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose|
|Abstract:||A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being one or more hydroxypropylmethylcelluloses or a mixture of one or more hydroxypropylmethylcelluloses and up to 30% by weight of the mixture of methylcellulose, sodium carboxymethylcellulose and/or other cellulose ether, and wherein at least one of the hydroxypropylmethylcelluloses has a methoxy content of 16-24 weight-%, a hydroxypropoxyl content of 4-32 weight-% and a number average molecular weight of at least 50,000 and wherein the carrier base material constitutes less than about one third of the weight of the solid unit dosage form.|
|Inventor(s):||Schor; Joseph M. (Locust Valley, NY), Nigalaye; Ashok (Jackson Heights, NY), Gaylord; Norman G. (New Providence, NJ)|
|Assignee:||Forest Laboratories, Inc. (New York, NY)|
Patent Claim Types:|
see list of patent claims
|Composition; Compound; Dosage form; Use;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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