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Serving hundreds of leading biopharmaceutical companies globally:

Cipla
Medtronic
Cantor Fitzgerald
Federal Trade Commission
Farmers Insurance
Covington
Argus Health
UBS
Deloitte

Generated: May 25, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,335,121

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Summary for Patent: 4,335,121
Title: Androstane carbothioates
Abstract:Compounds of the formula ##STR1## wherein R.sup.1 represents a fluoro-, chloro- or bromo-methyl group or a 2'-fluoroethyl group, R.sup.2 represents a group COR.sup.6 where R.sup.6 is a C.sub.1-3 alkyl group or OR.sup.2 and R.sup.3 together form a 16.alpha.,17.alpha.-isopropylidenedioxy group; R.sup.3 represents a hydrogen atom, a methyl group (which may be in either the .alpha.- or .beta.-configuration) or a methylene group; R.sup.4 represents a hydrogen, chlorine or fluorine atom; R.sup.5 represents a hydrogen or fluorine atom and symbol represents a single or double bond have good anti-inflammatory activity, particularly on topical applications. The compounds of formula I are prepared by esterification, halogenation, reduction, deprotection and reaction at a 9,11-double bond to form a 9.alpha.-halo-11.beta.-hydroxy grouping. Pharmaceutical compositions containing the compounds of formula I and methods for the use of the compounds are described and claimed.
Inventor(s): Phillipps; Gordon H. (Wembley, GB2), Bain; Brian M. (Chalfont St. Peter, GB2), Steeples; Ian P. (Ruislip Manor, GB2), Williamson; Christopher (Cobham, GB2)
Assignee: Glaxo Group Limited (London, GB2)
Application Number:06/234,113
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,335,121
Patent Claim Types:
see list of patent claims
Compound; Composition; Use; Process;

Drugs Protected by US Patent 4,335,121

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,335,121

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8005174Feb 15, 1980

International Family Members for US Patent 4,335,121

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Denmark 147022 ➤ Try a Free Trial
France 2477156 ➤ Try a Free Trial
Finland 70904 ➤ Try a Free Trial
Finland 810444 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Julphar
QuintilesIMS
McKinsey
Johnson and Johnson
Express Scripts
Teva
Covington
Harvard Business School

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