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Details for Patent: 4,128,658

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Summary for Patent: 4,128,658

Title: Aminoalkyl furan derivatives
Abstract:Compounds of the general formula I: ##STR1## and physiologically acceptable salts thereof and N-oxides and hydrates, in which R.sub.1 and R.sub.2 which may be the same or different represent hydrogen, lower alkyl, cycloalkyl, lower alkenyl, aralkyl or lower alkyl interrupted by an oxygen atom or a group ##STR2## in which R.sub.4 represents hydrogen or lower alkyl or R.sub.1 and R.sub.2 may, together with the nitrogen atom to which they are attached, form a heterocyclic ring which may contain other heteroatoms selected from O and ##STR3## R.sub.3 is hydrogen, lower alkyl, lower alkenyl or alkoxyalkyl; X is --CH.sub.2 --, O or S; Y represents .dbd. S, .dbd. O, .dbd. NR.sub.5 or .dbd. CHR.sub.6 ; Alk denotes a straight or branched alkylene chain of 1 to 6 carbon atoms; R.sub.5 is H, nitro, cyano, lower alkyl, aryl, alkylsulphonyl, or arylsulphonyl; R.sub.6 represents nitro, arylsulphonyl or alkylsulphonyl; M is an integer from 2 to 4; and N is 1 or 2; or when X .dbd. S, or --CH.sub.2 --, n is zero, 1 or 2. These compounds have H.sub.2 -antagonist activity. Intermediates in the production thereof are also provided.
Inventor(s): Price; Barry J. (Hertford, GB2), Clitherow; John W. (Sawbridgeworth, GB2), Bradshaw; John (Ware, GB2)
Assignee: Allen & Hanburys Limited (London, GB2)
Application Number:05/818,762
Patent Claim Types:
see list of patent claims
Compound; Composition; Dosage form; Use;

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Foreign Priority and PCT Information for Patent: 4,128,658

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom32465/76Aug 4, 1976
United Kingdom50685/76Dec 6, 1976
United Kingdom20187/77May 13, 1977

International Patent Family for Patent: 4,128,658

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
AustriaA574077<disabled in preview>
Austria375931<disabled in preview>
AustriaA322880<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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