Details for Patent: 4,128,658
✉ Email this page to a colleague
Summary for Patent: 4,128,658
| Title: | Aminoalkyl furan derivatives |
| Abstract: | Compounds of the general formula I: ##STR1## and physiologically acceptable salts thereof and N-oxides and hydrates, in which R1 and R2 which may be the same or different represent hydrogen, lower alkyl, cycloalkyl, lower alkenyl, aralkyl or lower alkyl interrupted by an oxygen atom or a group ##STR2## in which R4 represents hydrogen or lower alkyl or R1 and R2 may, together with the nitrogen atom to which they are attached, form a heterocyclic ring which may contain other heteroatoms selected from O and ##STR3## R3 is hydrogen, lower alkyl, lower alkenyl or alkoxyalkyl; X is --CH2 --, O or S;Y represents ═ S, ═ O, ═ NR5 or ═ CHR6 ;Alk denotes a straight or branched alkylene chain of 1 to 6 carbon atoms;R5 is H, nitro, cyano, lower alkyl, aryl, alkylsulphonyl, or arylsulphonyl;R6 represents nitro, arylsulphonyl or alkylsulphonyl;M is an integer from 2 to 4; andN is 1 or 2; or when X ═ S, or --CH2 --, n is zero, 1 or 2.These compounds have H2 -antagonist activity. Intermediates in the production thereof are also provided. |
| Inventor(s): | Barry J. Price, John W. Clitherow, John Bradshaw |
| Assignee: | Allen and Hanburys Ltd |
| Application Number: | US05/818,762 |
|
Patent Claim Types: see list of patent claims | Use; Composition; Dosage form; |
Drugs Protected by US Patent 4,128,658
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,128,658
International Family Members for US Patent 4,128,658
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Austria | 375931 | ⤷ Start Trial | |||
| Austria | 381937 | ⤷ Start Trial | |||
| Austria | A322880 | ⤷ Start Trial | |||
| Austria | A574077 | ⤷ Start Trial | |||
| Australia | 2751977 | ⤷ Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
