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|Title:||Pyrano[3,4-b]-indole derivatives, pharmaceutical compositions and methods of use|
|Abstract:||Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus bearing a substituent in position 1, said substituent incorporating an acid, ester or amide function therein, are disclosed. The nucleus is further substituted at position 1 and may be optionally substituted at positions 3, 4, 5, 6, 7, 8, and 9. The derivatives are useful antiinflammatory, analgesic, antibacterial and antifungal agents and methods for their preparation and use are also disclosed.|
|Inventor(s):||Demerson; Christopher A. (Montreal, CA), Humber; Leslie G. (Dollard des Ormeaux, CA), Dobson; Thomas A. (Dollard des Ormeaux, CA), Jirkovsky; Ivo L. (Montreal, CA)|
|Assignee:||American Home Products Corporation (New York, NY)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Dosage form; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|South Africa||72/3344||May 16, 1972|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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