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|Title:||Synthesis of 13-alkyl-gon-4-ones|
|Abstract:||The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.|
|Inventor(s):||Hughes; Gordon Alan (Wayne, PA), Smith; Herchel (Wayne, PA)|
|Assignee:||Smith; Herchel (Bryn Mawr, PA)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Process;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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